Faced with accelerating disruptions and social and environmental breakdowns, traditional forms of philanthropic giving may be less effective than they once were. Confronted with societal divisions, wars, and the climate crisis, core actors in philanthropy have begun to ask how philanthropy can respond more effectively in moments of a polycrisis. How can philanthropy deal with new forms of hypercomplexity? What is the role of philanthropy in responding to breakdown, and how can it promote regeneration and transformation?